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In multiple organisms, cellular NAD+ levels drop with age, which correlates with the onset of age-related conditions, including metabolic disorders, neurodegeneration, and cardiovascular problems

This includes vitamin K contained in multivitamins and combined vitamin D and K products

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At a glance, the table underscores the throughline of this entire comparison: none of these three compounds substitutes for another, because each is anchored to a different level of biological activity cellular, mitochondrial, and endocrine, respectively